| Molecular Formula | C19H17ClN4O2S |
| Molar Mass | 400.88 |
| Density | 1.51±0.1 g/cm3(Predicted) |
| Boling Point | 661.6±65.0 °C(Predicted) |
| pKa | 4.11±0.10(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Physical and Chemical Properties | Bioactive JQ-1 carboxylic acid is a ()-JQ1 derivative (a BET bromine domain inhibitor). JQ-1 carboxylic acid can be used as a precursor for synthetic PROTACs, targeting BET-bromine domain. |
| Use | Use of a highly efficient selective and cell-permeable BRD4 inhibitor. |
( )-JQ-1 is a potent, specific, and reversible BET bromodomain inhibitor, with IC 50 s of 77 and 33 nM for the first and second bromodomain (BRD4(1/2)). ( )-JQ-1 also activates autophagy.